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Overall, 68.4% (13/19) of children with café-au-lait macules and various other clinical presentations were molecularly confirmed with NF1. This study demonstrated that the majority …
The café-au-lait macules associated with NF type 1 and Leopard syndrome have increased proliferation of epidermal melanocytes (epidermal melanocytic hyperplasia). A café-au-lait macule is not classified as a …
Predictive value of cafe au lait macules at initial consultation in the diagnosis of neurofibromatosis type 1. Arch Dermatol, 145 (2009), pp. 883-887. ... Diagnostic value of …
Cafe-au-lait macules (CALMs) are common hyperpigmented and flat skin lesions found in the general population. They are usually present at …
Six or more café-au-lait macules over 5 mm in greatest diameter in prepubertal individuals and over 15 mm in greatest diameter in postpubertal individuals. Two or more neurofibromas of any type or one plexiform …
Solitary cafe-au-lait macules are benign lesions that are common in the general population (Figure 1, Figure 2). ... Patients should be questioned about other family members with multiple cafe-au-lait macules, …
The patient did not show café-au-lait macules, intertrigenous freckling, or Lisch nodules. The patient, a student, shows no signs of mental retardation or scoliosis. Her parents’ …
The first sign of neurofibromatosis type 1 (NF1) in a child is often the presence of multiple café-au-lait macules. Although previous studies reported that almost individuals with multiple café-au-lait macules will eventually …
Café-au-lait spots, occurring in more than 90% of NF1 cases, are sharply defined, light-brown, homogenous patches, which vary in diameter from 0.5 cm to 50 cm, with the …
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Mooresville. 76 miles: Kingsport (Tennessee) 70 miles: Black Mountain. 9 miles: North Wilkesboro. These are straight line distances in a radius around Purlear (North Carolina), …
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